Viagra Online at Canadian Pharmacy
Perhaps, the largest collection of Viagra info on the web. Generic Viagra Versions Review
Canadian Pharmacy www.canadianhealthcaremalll.com is your one-way stop for comprehensive information on all the Viagra-type medications available to the general public. The web is oozing with content on Viagra meds; however, a lion’s share of the info is marketing or sales-driven, especially if your queries are somewhat associated with buying the drug online. In aspiration to provide fair, in-depth info, we stand out from the crowd with the finest collection of materials on the topic: from indications for use and side effects overviews to all-inclusive researches focusing on a variety of aspects. We pay attention to every topic directly or indirectly related to the use of preparation, and stick to impartial provision of information. In addition, we aggregate myriads of real user reviews and testimonials from various sources, as we believe that the huge quantity gives quality to forming understanding in this or that area.
Another major scope of our attention falls on clinical researches: the comparative studies, clinical statistics, treatment effectiveness evaluations and other scientifically significant data. We are constantly replenishing our database of materials and introduce updates to keep it actual and up-to-date. Unlike a majority of our knowledgebase platforms, betting on amateur content, we run a team of specialists, representing our Canadian Pharmacy Research Lab division, that manually select, create and share content, providing value or verifying it beforehand. We also publish the info provided by our users, so if you like you have something to share, just contact us at your convenience. Finally, we are always ready to answer your questions on Viagra-like meds, feel free to reach us with your inquiries and our experts will reply shortly with detailed comments.
Sildenfil Citrate. PDE-5 action in a nutshell
The very first PDE-5 inhibitors representative, sildenafil citrate, has pushed ED treatment to the next level, heralding the era where PDE-5 preparations dominate the market. Sildenafil cleaves cGMP; with the oxide-nitric activation of pathways taking place during sexual stimulation, inhibition of PDE-5 leads to prevention of cGMP decay, the vital active component, leading to erection development. This drug represents the first line therapy means, it’s a safe and easy to use drug with the minimum of adverse reactions. As for the contraindications, the treatment must not be accompanied with nitrates intakes, the preparation is prescribed with caution to those people suffering from cardiovascular, kidney and liver diseases.
Clinical effectiveness of the substance has been evaluated in a variety of clinical trials conducted all around the world. One of the most comprehensive of them was conducted by Carson et al., aggregating the data obtained from 11 double-blind, placebo-controlled studies that involved as many as 3,000 patients with noteworthy erectile dysfunction symptoms. A 12-week clinical trial of sildenafil therapy enhanced erection in 76% of participants, outperforming the results in placebo group by 54%. The frequency of successful sexual intercourses has risen up to 66%, compared to 26% success rate in placebo group. The correlation between the effectiveness and the dosage taken is obvious; the improvement in sexual function was observed in the following proportions:
- 25mg of sildenafil – 65% improvement
- 50mg of sildenafil – 74% improvement
- 100mg of sildenafil – 82% improvement
Importantly, the preparation’s effectiveness is confirmed in both organic and psychogenic ED treatment. The high efficiency of sildenafil is confirmed in various age groups; thus, for example, the improvement in sexual health was achieved in 77.6% and 69.2% of cases in men under 65 years old.
Read about sildenafil citrate here: http://www.canadianhealthcaremalll.com/sildenafil-citrate
Treatment success is more than impressive. A look into clinical efficacy
According to Lue study conducted in 1997, the effectiveness of sildenafil ranges from 66 to 90% in cases of organic erectile dysfunction, observed with overall good tolerability. The drug’s efficacy in those suffering from diabetes ranges from 59 to 61%, hypertension – 64 – 70%, in depressive conditions – 58 – 77%, spinal cord injuries at the level T6-L4 – 65%. The high efficiency of the drug, as in psychogenic and organic ED forms, decent tolerability, extremely low frequency of significant adverse reactions, compatibility with a wide range of medications of different pharmacological groups – all of the above factors give strong grounds to consider sildenafil citrate to be one of the best pharmaceutical options in treatment of erectile dysfunction.
Another vital study conducted by Sairam et al. has confirmed a positive impact of sildenafil in treatment of urinary disorders in those males suffering from ED. The therapy lasting for 1-3 months results into a noteworthy reduction in lower urinary tract symptoms severity, observed simultaneously with considerable sexual health improvement. In recent years the action of sildenafil is explored and tested in other diseases treatment, the trend is gaining momentum.
Pressing for the optimal effect through precision in dosage selection
The average initial dosage ranges from 25 to 50 mg; however, the effect is individual, so the dosage must be adjusted if necessary to press for the optimal results. Both increases and decreases in dosage are possible, although the significant increases in dose must be negotiated with the treating doctor.
The drug’s effect is observed within 45 – 50 minutes after administration and lasts for 3 – 5 hours on average. The drug’s tolerance is referred to as good. The adverse reactions are more likely to occur in increased dosages; in Viagra it’s 100mg dose, accompanied by redness and headaches in 7% of cases, dyspepsia in 1.8% of patients, and blurred vision, observed in 1.2% of clinical cases. The most rare adverse reactions typically manifest as a result of treatment cessation, although there’s no withdrawal syndrome. The drug is considered to be widely accessible to patients from contraindications standpoint – Viagra treatment must not be initiated with coadministration of nitrates to exclude the risks of hypertension.
This way or the other, although the effectiveness of sildenafil is observed in 85% of cases, it doesn’t work perfectly in every case, and various studies claim that a relatively large group of patients admits the absence or insufficiency of effects (the numbers range from 9% to as high as 32%).
Generic Viagra at Canadian Pharmacy
Beginner’s Guide To Generic Viagra: http://www.canadianhealthcaremalll.com/generic-viagra
Despite the wide array of difficulties and challenges, generic market is gaining momentum at highly developed economy. In the UK and US the share of generic medications reaches nearly 50% from the total volume of pharmaceuticals, and there are dozens of prerequisites for the preservation of the trend. Branded medications are expensive. That’s a fact. But talking about the general concept of medicine, pharmaceuticals should be both effective and accessible. The paradox of gradually growing prices for various meds has plenty of explanations, but all and all there’s nothing you can do about it. Perhaps, with the exception of the only alternative – you can always take advantage of generic drugs.
With the introduction of the branded Viagra in 1998, the state of affairs around erectile dysfunction and its treatment has drastically changed: the neoteric PDE-5 inhibitor has quickly become the first choice medication in clinical practice due to its impressive efficacy, low risk of siginficant adverse reactions and a relatively short list of contraindications. However, the blue pill was and remains to be a pricey anti-ED tool: the cost of a single original pill starts from $20. The long term treatment can easily result into several hundred dollars expenses monthly – still, an inaccessible amount for a large share of males suffering from erectile dysfunction. Despite the release of improved formulations, Cialis and Levitra, the cost of the drug didn’t fall below the acceptable level. But fortunately, the price factor is no longer playing a decisive role in ED treatment as one can always take advantage of generic meds – making a choice in favour of generic Viagra means take advantage of the effective formulation at a significantly lower price against the background of the branded drug.
Game changing role of generics
The original manufacturer of Viagra claims the expenses associated with launching commercial sales of a Viagra-scale medications equal approximately $1bn. A closer look at the financial reports enables reveals the fact that a significant part of these resources is spent on marketing and sales activities, so the actual research work is not the most resource-intensive expenditure item. This way or the other, patenting, FDA approvals, clinical trials and other aspects still account for large expenses. Big Pharma companies are looking to cover their expenses and drive revenue, that’s why the price for the end product is typically high enough.
But that’s a completely different story with generics – such manufacturers take advantage of the patented, tested and approved formulation; thus, a larger part of expenses could be avoided. While more prominent generic manufacturers still undergo the approval process at FDA, smaller businesses just focus on manufacturing of drugs based on proven formulations. The bioequivalence factor, the most crucial one in generic drugs, defining how the drug is working in your body, should be no less than 85% in quality generic drugs, and if this result is achieved by manufacturers, the impact of the drug would be identical to the one provided by the branded pharmaceutical. Of course, there are certain risks of a weaker effect or higher frequency of side effects (mostly caused by lower quality auxiliary components and, as a result, lower cleanliness) in generic drugs, but this is where much depends on the manufacturer. If the drug is produced at modern facilities and the manufacturing process is well-optimized, the odds the results will be identical to the original product are more than just good.
The shopping challenge for everyone
With the advent of the web, shopping for generic ED drugs has become way simpler… and way more risky at the same time. The cost of manufacturing a generic product oftentimes goes far below $1 per unit, but the increasing demand is largely satisfied with poor quality or even hazardous products. To get the idea of the scope of demand, sildenafil is ranked 42th in the list of the overall pharmaceuticals sales in the US in 2014; the cost of generic Viagra starts from $2 in the web (the most accessible versions of really doubtful quality). So each time the customer jumps on the web to pick up some generic Viagra offer, there’s not only a risk of buying a low quality product, but also a risk of wasting your money – the unregulated area gave birth to zillions of scammers and fraudsters, getting more savvy and sophisticated in their techniques. Viagra, one of the highly demanded, has become the driver of unfair tactics on the rise of the web, and despite the agressive policies of search engines, the web didn’t become a safe place to buy it.
Currently, the seeds of fair shopping for drugs experience start growing – the platforms like Canadian Pharmacy aggregate myriads of diligent, time-tested drugstores that pass through a variety of inspections to confirm their status. That creates the ground for natural competition and safer shopping experience for customers, minimizing risks of non-delivered packages, wasted monies and hazardous medications to minimum. Moreover, the natural competition stimulates the development of customer service and such essential features as free professional consultations, expedited shipping options and, of course, totally affordable prices (4-5 times lower against the background of branded drugs).
Cheap in price, expensive in effect
Generic Viagra is based on the same active ingredient as the original medication – sildenafil citrate, although it may be different in terms of auxiliary components (more affordable materials may be used to cut off the manufacturing expenses). The drug is primarily designed to eliminate the symptoms of erectile dysfunction, although it is also used in pulmonary hypertension treatment. The drug is appointed to males only, and despite a number of studies revealing the positive effect in women, the use of sildenafil in females is contraindicated by the FDA. The mechanism of action lies in blockage of an enzyme that contributes to cGMP degradation, responsible for the blood flow in the body and blood flow to the penis in particular.
Generic Viagra helps you to eliminate erectile dysfunction problems like insufficient erection, premature ejaculation, sexual fatigue and less frequent issues (maintaining erection, prolonged period of times to build erection). The drug demonstrates impressive results in common people and those suffering from such diseases like diabetes and those having problems with kidneys. The drug demonstrates various degrees of effectiveness in 85% of cases, while the age factor is not that crucial when it comes to efficacy – according to clinical trials 65+ years old individuals achieved success in just 10% of cases less in comparison with the group of patients under 65 years old.
Just like the original preparation, generic Viagra therapy can cause adverse reactions of mostly non-serious nature. According to PubChem resource, collecting the data on pre-release and post-marketing clinical trials and surveys, the most common side effects are headaches, nausea and flushing, observed in up to 34%, 17% and 16% of cases, respectively. The medication is used with caution in those having serious cardiovascular system and liver conditions. Nitrates reception during Viagra therapy is strongly contraindicated for the risk of significant adverse reactions, that may lead even to a lethal outcome as a result of a sharp decrease in blood pressure.
Viagra Professional. The best in it`s kind.
Sildenafil citrate, the active substance of Viagra Professional, has modernized the ways of ED treatment – the impressively effective substance gave birth to the new category of drugs and acquired the status of the first line medication in ED therapy. Approved by the main pharmaceutical regulator in the US in 1998 the drug has climbed to the leadership positions of pharmaceuticals sales, now it occupies the 42nd place of the most purchased drugs in the country. Viagra Professional, the pioneer representative of PDE-5 inhibitors, is appointed to treat psychogenic, physiological and mixed types of ED. The preparation is designed to relax penile smooth muscles and increase the blood flow to male’s genitalia, which contributes to quality erections, better control and enhanced sexual endurance.
The medication is also used in treatment of pulmonary arterial hypertension and various diseases and conditions, not indicated in the insert. The experimental tests of the drug reveal a significant percentage of positive case where Viagra is used in complex therapy schemes, where the risks of lethal outcome are obvious. Scientists claim the potential of the drug yet has to be revealed and continue working on further developments. Thus, a new lineup of generic drugs focusing on ED treatment and targeting premature ejaculation in particular was released. A series of generic meds is based on dapoxetine and sildenafil, allowing the patient to deal with the issue safely and effectively. Viagra Professional, in its turn, represents the most powerful option of generic Viagra available in the market: the drug comes with 100mg of sildenafil on board, the dosage that has proved the most impressive results in 21 randomized clinical trials with more than 3,000 participants (reportedly, the success rate equaled 84%).
More about Viagra Professional: http://www.canadianhealthcaremalll.com/viagra-professional
The formula of success
Despite the widespread, deeply rooted misconceptions, Viagra does not provide a stimulative effect on the libido, neither it triggers sexual arousal – the drug’s effect is only manifested in the event of natural excitation. If this is the case, the erectile dysfunction symptoms caused by physiological or psychological problems could be eliminated and the chance for conducting a full sexual intercourse increase dramatically.
Under the influence of natural excitation, central nervous system launches the production of nitric oxide, the substance stimulating enzymes, which in their turn excrete cyclic guanosine monophosphate compound. The compounds (cGMP) action lies in producing a relaxing effect on penile muscles. In the event of the absence of sexual health problems, this process leads to filling the penis with sufficient amount of blood through penile arteries, contributing to erection.
However, in the presence of ED problems, this process could be violated at some stage, preventing the blood from entering genitalia. Viagra Professional enables your body to take control over cGMP production, preserving the capacity of the arteries and their functioning. The effectiveness of the reception greatly depends on the level of sexual excitation, the process that involves NO production; so if the substance is not released in the body, the results will leave much to be desired.
Against the background of placebo, the therapeutic action of Viagra is noteworthy – in the most comprehensive clinical trials involving patients of various age groups, the effectiveness rate in inactive medicine didn’t exceed 22%, while clinical trials in Viagra showed an impressive results rate of 84%.
Contraindications and side effects. The dark side of Viagra treatment
The drug’s reception inevitably leads to lowering of blood pressure. Therefore, during Viagra therapy you should exclude the reception of nitrate drugs that produce a similar impact on your blood pressure and may even lead to lethal consequences as a result of severe circulatory disorders. The use of Viagra is contraindicated in women and individuals under 18 years old. The preparation is prescribed with caution in the elderly and those suffering from renal failure.
Viagra Professional is considered to be a relatively safe preparation with the minimum risk of significant side effects. In various clinical trials the drug’s adverse reactions were observed in up to 10% of participants; the similar numbers were observed in post-marketing researches. However, the nature of the side effects (headaches, nausea, running nose, blurry vision, etc.) were observed in a tiny fraction of respondents and had temporary, non-severe nature.
Beast Power. How to take Viagra to make the most of your sexual experience
The onset of drug’s action is typically observed within 45 – 60 minutes and preserved for up to 4 hours (although there were cases in clinical trials where the effect was preserved up to 6 hours in 100mg dosage – the amount Viagra Professional contains). The drug is ideally taken on empty stomach to accelerate absorption, when it is taking with plenty of meals or fatty foods, the onset of action as well as its power may be adversely impacted. The optimal dose is individually calculated according to the age and degree of erectile dysfunction, 100mg dosage guarantees the best results according to clinical trials.
Viagra Super active+. An old good formulation that works even better
Sexual health – is an important component of the overall emotional and physical health of any person. Preserving it at a high level throughout life is an essential priority of any men. If you are having problems with erection, its maintenance or collide with premature ejaculation on a regular basis, it is highly likely you are suffering from erectile dysfunction that may pass on the background of even more complicated disease. If the problems have a recurring nature, you must seek for professional medical assistance as soon as possible, as erectile dysfunction is best treated at the early stages. If the diagnosis is confirmed, the chance that you’ll be assigned Viagra based preparation is very high – the drug represents the first line choice in medications. Viagra Super Active+ is an improved formulation that leaves nothing to be desired in terms of efficacy – definitely, that’s the best Viagra can do. So let’s take a closer look at the drug.
Viagra Super Active+ mechanisms of action in focus
Viagra Super Active+, just like its parent drug, is based on sildenafil citrate, is the pioneer of PDE-5 inhibitors group and primarily designed to normalize sexual function in men. Unlike other previously used methods involving injections into the penis or other medical procedures, Viagra is a simple, easy-to-drug use: you need to take a pill before anticipated sexual activity. Viagra is neither an aphrodisiac, nor erection stimulant – it works in response to natural sexual stimulation, allowing you to achieve a natural erection and maintain it at the required level to conduct full sexual intercourse.
Read about viagra super active here: http://www.canadianhealthcaremalll.com/viagra-super-active
So this is how Viagra boosts your sexual power
Understanding the mechanisms of Viagra functioning requires understanding the basic principles of how erection works. When a person is sexually aroused, the brain sends a signal to the nerve endings in the tissues of the genitalia, which leads to the expansion of penis blood vessels and a considerable increase in blood flow, contributing to an erection: the vessels are narrowed, allowing the blood flow reach genitalia in the sufficient quantity to guarantee stable erection. The combination of increased blood flow and its reduced outflow leads to full erection. After the sexual intercourse the penis returns into its normal state; however, the time for recovery until the next sexual intercourse is decrease. The preparation enables you to combat sexual fatigue and insufficient erections, as well as premature ejaculation and poor erection maintenance.
Increase your chances to make it work better
The preparation is appreciated for the simplicity of its administration. Take a pill of Viagra Super Active+ an hour before the anticipated sexual intercourse; in the process of time you will adjust the dosage and select the optimal time frame for reception. In around 40 – 60 minutes, Viagra will start responding to sexual stimulation and will help you to build strong erection. The effect of the drug lasts for no more than 4 hours; although there are clinical cases where it lasts up to 6 hours and more – that’s a particular feature of the highest dosage, 100mg (the one Super Active+ modification provides). This way or the other, sexual activity can be initiated in a period between 30 minutes – 3.5 hours after administration of the pill on average. It is preferably to take Viagra on empty stomach, which guarantees a faster absorption and lowers the risk of insufficient effect (if the drug is taken after or with meals, especially if you eat fatty foods, your body will need more time to absorb the active substance). The maximum daily dosage must not exceed 100mg.
What should you expect from Super Active formulation?
Viagra Super Active+ comes in the form of 100mg pills, providing the best efficacy results in all the erectile dysfunction types. High efficiency and safety of Viagra has been proven in more than 120 large-scale clinical trials around the world. In 100mg dosage the improvements of various degree in sexual function are observed in 82 – 86% of males of 19 – 78 years old group. When taking Viagra for the first time do not expect to get the results – evaluate the efficacy of the drug after the 5th intake. In the event of poor efficiency, consult your therapist on the matter of reconsidering the treatment approaches.
Does Viagra fit in ‘one fits all’ concept?
Viagra is a relatively safe medication. However, just like in any pharmaceutical drug, Viagra therapy is not deprived of side effects. The most common adverse reactions are headaches, flushing and upset stomach; they are observed in less than 10% of cases and have a non-aggressive nature, while the risk of significant adverse effects doesn’t go beyond 2%. In a small percentage of men changes in vision and blurry vision may be observed: the objects may acquire a blue tint, and the sensitivity to light can be increased. Typically, the duration of these reactions ranges from several minutes to one hour. It should be remembered that in sexual activity itself can have a strain on the heart. If the condition of your heart causes concerns, consult your physician before increasing sexual activity.
The preparation is prescribed with caution to the elderly and those suffering from cardiovascular and kidney diseases, as well as in case of renal impairment. Despite some positive data in experimental trials, the preparation is strongly contraindicated in women; neither the drug is approved for use in adolescents under 18 years old. The drug must not be taken simultaneously with nitrates (such as nitroglycerin) to exclude the risks of severe adverse reactions and even lethal outcomes. The drug is not compatible with alcohol because of the risk of significant side effects.
By Canadian Health&Care Pharmacy www.canadianhealthcaremalll.com
